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However, a person can receive anticoagulant medications and LR at the same time, as long as a medical professional delivers each treatment through a separate IV line. Mixing citrate with calcium can cause blood clotting and obstruct an IV line. The reason for this concern was that some anticoagulant, or blood-thinning, medications contain citrate, while LR contains high levels of calcium. In previous years, some medical professionals expressed concern over using LR during blood transfusions. If a person with any of these conditions requires LR or saline, a medical professional will monitor them closely for signs of hypervolemia. IV fluid administration further increases the risk of hypervolemia and associated swelling and edema. The above health conditions reduce the body’s ability to remove excess fluid.
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For instance, these devices can be faulty, or software or electrical issues can occur. According to the Food and Drug Administration (FDA), many of the reported problems with fluid infusion are due to electric pump use.

With the electric pump method, a healthcare professional programs an electric pump to deliver the correct dosage of LR automatically. They may also count the number of drops per minute to ensure an accurate and safe flow.
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With the manual technique, a healthcare professional adjusts the pressure of the clamp on the IV tube to reduce or facilitate the flow rate. Medical professionals may administer LR in one of two ways: manually or via an electric pump.

IV fluid regulation refers to the monitoring and control of how much fluid passes from the bag into the bloodstream. The fluid will pass from an external IV bag, through an IV line, and into the bloodstream. LR is an IV medication, meaning that a doctor or trained nurse will administer it into a vein. These included:Īlthough both LR and saline are equally effective in most clinical settings, research suggests that LR might be more effective for trauma patients experiencing burns or excessive blood loss. The researchers found no statistically significant difference between the two groups for any of the variables that they measured. In addition, it is formulated with sodium lactate to promote the metabolization of bicarbonate, thereby lowering acidity in the body.Ī 2020 study involving people who had undergone colorectal or orthopedic surgery investigated the difference in outcomes between people receiving LR and those getting the equivalent volume of saline solution. LR does not last as long in the body, so it is less likely to cause fluid overload, known as hypervolemia. LR and saline differ in terms of their chemical content and their overall effects on the body.
